Chart 1. – Clinical score for suspecting FCS.

Criterium	Score
Fasting triglycerides ≥ 1,000 mg/dL in 3 not necessarily consecutive analyses	+ 5
* Fasting triglycerides at least once ≥ 1,760 mg/dL	+ 2
Previous triglycerides < 200 mg/dL	- 5
No secondary factors, except for pregnancy and ethinylestradiol	+ 2
History of pancreatitis	+ 1
Unexplained recurrent abdominal pain	+ 1
No history of familial combined hyperlipidemia	+ 1
No response to lipid-lowering treatment (triglyceride decrease < 20%)	+ 1
Symptom onset at age:
< 40 years	+ 1
< 20 years	+ 2
< 10 years	+ 3
FCS score
Very likely	≥ 10
Unlikely	≤ 9
Very unlikely	≤ 8

FCS: familial chylomicronemia syndrome. * Only if the previous criterium (fasting triglycerides ≥ 1,000 mg/dL in 3 not necessarily consecutive analyses) is positive. Adapted from Moulin et al. Atherosclerosis 2018; 2018;275:265-272. ²¹