Figure 2.
Changes in lipids and apolipoproteins subspecies in the VLDL fraction from baseline to 2 years according to tertiles of blood regional DNA methylation level at CPT1A in low- and high-fat diet group. Models were adjusted for age, sex, use of lipid-lowering medication, baseline body mass index, baseline values of the respective outcomes, and concurrent weight loss. Panel A: Triglycerides in VLDL with apoC-III; B: Cholesterol in VLDL with apoC-III; C: apoB in VLDL with apoC-III; D: apoE in VLDL with apoC-III; E: Triglycerides in VLDL without apoC-III; F: Cholesterol in VLDL without apoC-III; G: apoB in VLDL without apoC-III; H: apoE in VLDL without apoC-III. Sample size for lipids and apolipoproteins subspecies in low-fat group: T1, n = 40; T2, n = 48; T3, n = 44 (except for TG in VLDL with apoC-III, n = 43); high-fat group: T1, n = 53; T2, n = 54 (except for apoB in VLDL with apoC-III, n = 53); T3, n = 44.
