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. Author manuscript; available in PMC: 2024 Jan 1.
Published in final edited form as: Harv Rev Psychiatry. 2023 Jul-Aug;31(4):183–194. doi: 10.1097/HRP.0000000000000373

Table 1:

Main Classes of medications used in Gender Affirming Hormone Therapy regimens

Main Sex Steroids Pubertal Suppressants, i.e., Gonadotropin-Releasing Hormone Agonists (GnRHas)  Anti-androgens Other
Estradiol 
Testosterone
Leuprolide (Lupron, Eligard)
Triptorelin (Decapeptyl)
Histerelin (Supprelin LA)
Goserelin (Zoladex)
Spironolactone
GnRHas 
Cyproterone acetate (internationally)
Progesterone (often in conjunction with estradiol)
Norethindrone, norethisterone (for menstrual suppression)