Table 3:

CYP and drug-drug interactions for Testosterone

Medications that May Increase Testosterone Levels	Medications that May Decrease Testosterone Levels
CYP3A4 Inhibitors Fluvoxamine, Nefazodone, Suboxone CYP2C19 Inhibitors Progesterone, Fluvoxamine CYP2C9 Inhibitor Fluoxetine  CYP2C6 Inhibitors Bupropion, fluoxetine, paroxetine	CYP3A4 Inducers Modafinil, St. John’s Wort, Tobacco, Topiramate CYP2C19 inducer Carbamazepine CYP2C9 inducer Carbamazepine  Enzyme-inducing AEDs Carbamazepine, oxcarbazepine, topiramate, phenobarbital