Figure 4.

The changes in immunophenotyping before and after CB-NK cell treatments were analyzed. The results revealed a marked improvement in immunity, evidenced by a decrease in the number of abnormal phenotypes. Administration of CB-NK cells was associated with a significant increase in lymphocytes (CD14^Low), T cells (CD3⁺), helper T cells (CD3⁺CD4⁺), naïve CD4⁺T cells (CD3⁺CD4⁺CD27⁺CD45RA^-), effector memory CD4⁺T cells (CD3⁺CD4⁺CD27^-CD45RO⁺), myeloid dendritic cells (DC, Lineage^-CD11c⁺HLA-DR⁺), and lymphoid DC (Lineage-CD123⁺ HLA-DR⁺). Furthermore, CB-NK cell therapy was also associated with a decrease in the number of monocytes (CD14⁺) and granulocytes (CD14^high) and naïve CD8⁺T cells. Red line represents the reference value.