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. 2023 Jul 14;18(7):e0288598. doi: 10.1371/journal.pone.0288598

Table 3. Difference in change from baseline in metabolic and liver parameters for the maraviroc + OBT versus OBT group with bootstrapped 95% confidence intervals.

  Week Number of participants Difference between MVC+OBT / OBT groups in change from baseline 95% LCL 95% UCL
BMI, kg/m2 48 45 0.1 -0.7 0.8
  96 45 0.1 -0.5 0.7
Waist circumference, cm 48 43 2.6 -4.0 9.2
  96 42 1.5 -6.4 9.3
CD4 cell count, cells/mm3 48 45 70 -39 179
  96 44 -47 -133 39.4
Fasting glucose, mmol/L 48 44 0.0 -0.8 0.7
  96 42 0.8 -0.5 2.2
HbA1c, mmol/mol 48 45 -2.3 -6.7 2.1
  96 45 2.5 -2.6 7.7
AST, U/L 48 43 -0.5 -6.9 5.9
  96 38 7.0 -2.8 16.8
ALT, U/L 48 44 -5.7 -21.1 9.7
  96 45 0.5 -19.8 20.7
Fasting triglycerides, mmol/L 48 44 0.7 0.0 1.4
  96 46 -0.2 -1.0 0.6
Fasting LDL, mmol/L 48 40 0.0 -0.4 0.4
  96 41 0.0 -0.4 0.5
Fasting HDL, mmol/L 48 44 0.0 -0.1 0.2
  96 46 0.1 -0.1 0.3
Fasting HDL: total chol. ratio 48 44 0.3 -0.6 1.1
  96 46 -0.3 -1.0 0.4
Fasting total chol., mmol/L 48 44 0.1 -0.4 0.6
96 46 0.1 -0.4 0.6
Fibroscan median LS, kPa 48 43 -1.7 -3.7 0.4
  96 41 -0.6 -2.4 1.2
Fibroscan CAP score, dB/m 48 41 -15.1 -57.8 27.6
  96 39 -5.8 -40.0 28.5
ELF score 48 43 0.3 0.0 0.6
  96 42 0.1 -0.3 0.5

LCL, lower confidence limit; UCL upper confidence limit