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. 2023 Jul 14;18(7):e0288605. doi: 10.1371/journal.pone.0288605

Table 3. Threshold values of influential parameters on the model results of a cost-effective strategy.

Variable Base-case value Threshold value Change of preferred cost-effective strategy (WTP = 7,055 USD/DALY)
Sensitivity of AlereLAM 34.90% >65.12% AlereLAM +Xpert Ultra
Sensitivity of FujiLAM 70.70% <40.48% AlereLAM +Xpert Ultra
Sensitivity of Xpert for MTB detection 74.90% >98.05% Xpert
87.58%-98.05% FujiLAM + Xpert
Sensitivity of Xpert Ultra for MTB detection 87.60% >98.05% Xpert Ultra
<74.94% FujiLAM + Xpert
Sensitivity of Xpert Ultra for rifampicin resistance 94.90% <71.10% FujiLAM + Xpert
Specificity of Xpert Ultra for rifampicin resistance 99.10% <90.50% FujiLAM + Xpert

DALY: disability-adjusted life years; MTB: Mycobacterium tuberculosis; WTP: willingness-to-pay