Table 4. Antimicrobial resistant profile of DEC pathotypes (n = 183) isolated from diarrheic and non-diarrheic children under age five in Addis Ababa and Debre Berhan, Ethiopia.
Antibiotics class | Antibiotics | EPEC (n = 28) | ETEC (n = 39) | EIEC (n = 23) | EAEC(n = 76) | Hybrid (n = 13) | Others (n = 4) | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
R | S | R | S | R | S | R | S | R | S | R | S | ||
Penicillin | Ampicillin | 89% | 11% | 92% | 8% | 91% | 9% | 99% | 1% | 100% | 0% | 100% | 0% |
Beta lactam combination | Amoxicillin-Clavulanate | 7% | 93% | 10% | 90% | 4% | 96% | 11% | 90% | 0% | 100% | 0% | 100% |
Fluoroquinolone | Ciprofloxacin | 4% | 96% | 15% | 85% | 9% | 91% | 22% | 78% | 8% | 92% | 0% | 100% |
Aminoglycoside | Gentamicin | 7% | 93% | 26% | 74% | 13% | 87% | 41% | 59% | 15% | 85% | 100% | 0% |
Sulphonamides | trimethoprim-sulfamethoxazole | 14% | 86% | 33% | 67% | 39% | 41% | 58% | 42% | 31% | 69% | 100% | 0% |
Phenicol | Chloranphenicol | 7% | 93% | 23% | 77% | 9% | 91% | 37% | 63% | 23% | 77% | 100% | 0% |
Tetracycline | Tetracycline | 89% | 11% | 92% | 8% | 91% | 9% | 92% | 8% | 85% | 15% | 100% | 0% |
Cephalosporin | Ceftazidime | 11% | 89% | 15% | 85% | 9% | 91% | 20% | 80% | 8% | 92% | 75% | 25% |
Cefotaxime | 11% | 89% | 15% | 85% | 9% | 91% | 20% | 80% | 8% | 92% | 75% | 25% | |
Cefepime | 4% | 96% | 3% | 97% | 0% | 100% | 7% | 93% | 8% | 92% | 0% | 100% | |
Carbapenem | Meropenem | 0% | 100% | 5% | 95% | 0% | 100% | 3% | 97% | 0% | 100% | 0% | 100% |
Ertapenem | 0% | 100% | 5% | 95% | 0% | 100% | 3% | 97% | 0% | 100% | 0% | 100% |
DEC, Diarrheagenic Escherichia coli; EPEC, Enteropathogenic Escherichia coli; ETEC, Enterotoxigenic Escherichia coli; EIEC, Enteroinvasive Escherichia coli; EAEC, Enteroaggregative Escherichia coli; Others, Shiga-toxin producing Escherichia coli (STEC) and Diffusely adherent Escherichia coli (DAEC), R, Resistance; S, Susceptible