Table 1. Wfs1 deficiency leads to dampened locomotor rhythm.

Genotype	Period±SEM (hour)	Power±SEM	Rhythmicity	N
Uwfs1RNAi#1/+	23.71±0.03	63.20±3.82	95%	75
Uwfs1RNAi#2/+	23.69±0.03	58.70±4.04	95%	65
tubG4/+	24.12±0.04	74.3±5.99	88%	57
tubG4/Uwfs1RNAi#1	24.25±0.13	8.00±2.41*** ###	30%	27
tubG4/Uwfs1RNAi#2	24.28±0.17	22.17±5.43** ###	60%	15
elavG4	23.84±0.04	49.42±3.47	83%	77
elavG4;Uwfs1#1/+;MM	23.71±0.05	59.13±5.69$ $ $	88%	48
elavG4;M/M	23.53±0.11	18.00±4.51###	43%	42
elavG4;Uwfs1#1/+	23.78±0.06	74.85±5.41##	97%	35
Uwfs1/+	23.65±0.04	69.75±7.89	86%	35
elavG4;Uwfs1RNAi#1/+	23.87±0.06	24.35±3.46*** ###	70%	43
elavG4;Uwfs1RNAi#2/+	23.96±0.11	10.24±2.53*** ###	33%	36
Udcr2/+;repoG4/+	23.92±0.11	56.51±7.12	91%	47
Udcr2/Uwfs1RNAi#1;repoG4/+	23.69±0.07	72.62±7.45	100%	24
Udcr2/Uwfs1RNAi#2;repoG4/+	23.79±0.08	64.19±6.04	100%	34
Udcr2/+;cryG4-16/+	24.90±0.09	46.04±7.16	86%	28
Udcr2/Uwfs1RNAi#1;cryG4-16/+	24.46±0.08	65.14±5.37	100%	26
Udcr2/Uwfs1RNAi#2;cryG4-16/+	24.50±0.06	63.70±6.61	88%	32
timG4/+	24.44±0.04	47.15±6.06	76%	33
timG4/wfs1RNAi#1	24.33±0.06	66.63±7.51	84%	31
timG4/wfs1RNAi#2	24.36±0.04	76.38±6.72	93%	43
WT	23.73±0.04	50.80±4.85	82%	62
M/M	23.62±0.04	33.31±4.38@@@	47%	95
Dop2RG4	23.70±0.04	62.19±4.74	83%	84
Dop2RG4;Uwfs1RNAi#1/+	23.78±0.05	29.69±3.66*** ###	57%	90
Dop2RG4;Uwfs1RNAi#2/+	24.16±0.32	21.35±3.41*** ###	43%	82
GαoG4/+	23.85±0.09	36.60±5.35	70%	37
GαoG4/Uwfs1RNAi#1	23.72±0.15	7.55±2.86 *** ###	32%	28
GαoG4/Uwfs1RNAi#2	24.00±0	1.41±0.73 *** ###	5%	21
UGFPRNAi/+	23.61±0.04	75.71±10.04	95%	23
tubG4/UGFPRNAi	24±0.03	60.97±7.37	82%	34
elavG4;Udcr2/+	23.78±0.07	76.02±8.63	100%	20
elavG4;Udcr2/UGFPRNAi	23.82±0.07	77.96±9.19	91%	24
Udcr2/UGFPRNAi;repoG4/+	23.78±0.07	88.82±8.88##	100%	32

One-way ANOVA, #/*P < 0.05, ##/**P < 0.01, ###/***P < 0.001. Mann-Whitney test, ###/$ $ $/@@@P < 0.001. # compared with the GAL4 controls; * compared with the UAS controls; $ compared with GAL4 under mutant background; @ compared with WT. G4, GAL4; U, UAS; M, wfs1^MI14041.