TABLE 6.

Cutoff Value, Sensitivity, Specificity, Accuracy, and AUC of Each Quantitative MRI Parameter to Estimate IDH Mutation Status

MRI Parameters	Reader 1	Reader 2
Maximum tumor size
Cutoff value	≤45.1	≤41.0
Sensitivity	61.9%	42.9%
Specificity	62.1%	71.7%
Accuracy	62.1%	69.8%
AUC	0.578 (0.451–0.704)	0.54 (0.398–0.682)
Mean ADC
Cutoff value	≥1.014	≥0.976
Sensitivity	55.0%	85.0%
Specificity	70.3%	40.7%
Accuracy	69.3%	43.5%
AUC	0.548 (0.383–0.712)	0.61 (0.486–0.734)
Minimum ADC
Cutoff value	≥1.014	≥0.866
Sensitivity	45.0%	75.0%
Specificity	74.7%	45.9%
Accuracy	72.8%	47.7%
AUC	0.533 (0.364–0.701)	0.539 (0.412–0.665)

Data in parentheses are 95% CIs.