TABLE 3.
IMPACT-III and multi fatigue dimension scale
| Exercise period (n = 15 children, n = 24 parents) | Control period (n = 7 children, n = 12 parents) | |||||||
|---|---|---|---|---|---|---|---|---|
| Before | After | P values | Before | After | P values | Effects size vs controls | P value | |
| [95% CI] | Exercise vs control | |||||||
| IMPACT-III | ||||||||
| Total score | 79 [71–81] | 81 [75–89] | 0.006 * | 79 [73–85] | 70 [56–86] | 0.108 | 13 [4 to 8] | 0.006 * |
| Bowel symptoms | 75 [61–86] | 82 [71–86] | 0.017 * | 79 [64–82] | 50 [46–93] | 0.115 | 13 [1.3 to 25] | 0.029 * |
| Body image | 67 [67–83] | 75 [67–92] | 0.258 | 67 [50–83] | 67 [58–92] | 0.276 | 17 [2 to 31] | 0.679 |
| Social functioning | 83 [75–92] | 88 [79–92] | 0.173 | 81 [71–85] | 73 [65–83] | 0.498 | 9 [5 to 18] | 0.036 * |
| Systemic symptoms | 67 [33–75] | 75 [58–75] | 0.147 | 58 [50–75] | 67 [8–75] | 0.350 | −3 [−16 to 10] | 0.433 |
| Emotional functioning | 82 [71–86] | 86 [75–93] | 0.100 | 82 [79–93] | 79 [57–93] | 0.138 | 13 [−19 to 44] | 0.029 * |
| Treatment | 75 [67–92] | 83 [83–100] | 0.082 | 92 [67–100] | 67 [42–83] | 0.026 * | 26 [17 to 36] | <0.001 * |
| MFS child report | ||||||||
| General fatigue | 70.8 [50–79.2] | 70.8 [66.7–79.2] | 0.084 | 62.5 [50–83.3] | 75 [33.3–95.8] | 0.497 | 1 [−23 to 25] | 0.945 |
| Sleep/rest fatigue | 58.3 [50–70] | 66.7 [50–75] | 0.346 | 70.8 [50–87.5] | 62.5 [54.2–75] | 0.345 | 5 [−11 to 22] | 0.533 |
| Cognitive fatigue | 75 [55–91.7] | 75 [66.7–87.5] | 0.475 | 70.8 [66.7–91.7] | 91.7 [55–91.7] | 0.463 | −5 [−20 to 10] | 0.542 |
| Total score | 70.8 [50–79.2] | 70.8 [66.7–79.2] | 0.367 | 68.1 [56.9–87.5] | 72.2 [55.6–87.5] | 0.917 | 0 [−15 to 15] | 0.990 |
| MFS parent report | ||||||||
| General fatigue | 56 [41.7–69.8] | 70.8 [55.2–78.1] | 0.004 * | 60.4 [54.2–72] | 54.2 [31.3–74] | 0.783 | 18 [−1.3 to 37] | 0.069 |
| Sleep/rest fatigue | 54.2 [39.6 –72.9] | 66.7 [50–82.3] | 0.044 * | 69 [56.9–82.3] | 56.3 [39.6–82.3] | 0.126 | 13 [−2.4 to 28.4] | 0.098 |
| Cognitive fatigue | 75 [53.1–94.8] | 75 [54.2–95.8] | 0.433 | 79.2 [75–100] | 81.3 [56.3–100] | 0.390 | 6.7 [−1.1 –14.4] | 0.092 |
| Total score | 62.5 [49.7–74] | 71.5 [58.7–82.3] | 0.015 * | 68.2 [61.8–82.6] | 64.6 [52.8–83.7] | 0.533 | 14 [0.1 to 30] | 0.048 * |
Values are shown in mean ± SD or as median [IQR]. P values were measured using paired t testing (parametric data) or Wilcoxon rank sum test (nonparametric data).
MFS = Multidimensional Fatigue Scale.
*
= P < 0.05.