Table 4.
Predictors of pathological c-IMT (≥0.90 mm). Univariate analysis.
| Subjects with c-IMT≥0.90 mm (n = 195) OR (CI%95) | p-value | |
|---|---|---|
| Age (years) ≥ 65 | 4.41 (3.07–6.34) | < 0.001 |
| Men (%) | 1.92 (1.35–2.74) | < 0.001 |
| Non–smokers | 0.82 (0.57–1.17) | 0.276 |
| Current Smokers (%) | 1.00 (0.64–1.55) | 0.986 |
| Ex–smokers (%) | 1.18 (0.85–1.63) | 0.318 |
| Hypertension (%) | 3.47 (2.32–5.20) | < 0.001 |
| Dyslipidemia (%) | 0.49 (0.50–1.25) | 0.329 |
| Diabetes (%) | 2.34 (1.68–3.28) | < 0.001 |
| Obesity (%) | 1.10 (0.79–1.52) | 0.553 |
| Sedentary (%) | 0.92 (0.65–1.30) | 0.660 |
| Metabolic Syndrome (%) | 3.06 (2.19–4.28) | < 0.001 |
| CV event (%) | 3.08 (2.18–4.34) | < 0.001 |
| SBP (mmHg) ≥ 140 | 1.77 (1.27–2.46) | 0.001 |
| DBP (mmHg) ≥ 90 | 0.55 (0.35–0.85) | 0.008 |
| PP (mmHg) ≥ 60 | 3.19 (2.26–4.49) | < 0.001 |
| TC (mg/dL) ≥ 190 | 0.57 (0.39–0.83) | 0.004 |
| LDL (mg/dL) ≥ 100 | 0.52 (0.37–0.74) | < 0.001 |
| Triglyceride (mg/dL) ≥ 200 | 0.82 (0.52–1.30) | 0.416 |
| FPG (mg/dL) ≥ 126 | 1.63 (1.11–2.40) | 0.013 |
| HbA1C (%) ≥ 6.5 | 1.63 (1.11–2.40) | 0.011 |
| eGFR (ml/min) < 60 | 1.54 (1.06–2.25) | 0.023 |
| Antihypertensive drugs | 5.09 (3.08–8.41) | < 0.001 |
| Lipid lowering drugs | 1.26 (0.79–2.01) | 0.321 |
| Antidiabetic drugs | 1.89 (1.36–2.63) | < 0.001 |
CV, cardiovascular; DBP: Diastolic Blood Pressure; FPG, fast plasma glucose; HbA1c, glycated hemoglobin; HDL, high–density lipoprotein; LDL, low–density lipoprotein; PP, pulse pressure; SBP, systolic blood pressure; TC, total cholesterol. Bold means statistically significant values.