TABLE 1.
Demographic characteristics of the study population.
| AD | Old | Young | p-value | |
|---|---|---|---|---|
| Platelet activation | n = 11 | n = 18 | n = 10 | |
| Sex female, n (%) | 7 (64%) | 9 (50%) | 3 (30%) | |
| Age range, years | 61–83 | 64–76 | 18–25 | |
| Age, years, mean (SD) | 74.4 (7.2) | 69.5 (2.6) | 20.8 (2.1) | 0.0327 |
| MMSE a , mean (SD) | 21.7 (4.0) | 28.0 (0.0) | n.d. | <0.0001 |
| Proteomics | n = 7 | n = 7 | n = 9 | |
| Sex female, n (%) | 5 (71%) | 3 (43%) | 2 (22%) | |
| Age range, years | 61–80 | 70–76 | 18–25 | |
| Age, years, mean (SD) | 73.1 (7.5) | 71.4 (2.1) | 20.9 (2.3) | 0.2413 |
| MMSE a , mean (SD) | 20.0 (4.8) | 28.0 (0.0) | n.d. | 0.0010 |
| Transcriptomics | n = 9 | n = 9 | n = 9 | |
| Sex female, n (%) | 5 (56%) | 5 (56%) | 2 (22%) | |
| Age range, years | 61–83 | 64–76 | 18–25 | |
| Age, years, mean (SD) | 74.2 (7.8) | 70.4 (2.6) | 21.0 (2.2) | 0.1776 |
| MMSE a , mean (SD) | 20.8 (4.2) | 28.0 (0.0) | n.d. | 0.0002 |
a
Mini-Mental State Examination (MMSE). In Old controls, MMSE, score was predicted using the Salzburg Dementia Test Prediction (SDTP). P-value indicates statistical differences between AD, and Old groups (age: Mann-Whitney test; MMSE: unpaired t-test). Significant p-values (<0.05) are highlighted in bold.