TABLE 1.
Primary Outcomes
| Fluid Dose Administered | Lactate Normalization, n (%) | OR | p | |
|---|---|---|---|---|
| No | Yes | |||
| All | 1,275 (85.5) | 216 (14.5) | ||
| < 15 cc/kg IBW | 325 (87.6) | 46 (12.4) | 0.969 | 0.268 |
| 15–25 cc/kg IBW | 243 (87.4) | 35 (12.6) | 0.955 | 0.121 |
| Reference: 25.1–35 cc/kg IBW | 258 (81.6) | 58 (18.4) | — | — |
| 35.1–50 cc/kg IBW | 265 (83.1) | 54 (16.9) | 0.993 | 0.813 |
| > 50 cc/kg IBW | 184 (88.9) | 23 (11.1) | 0.939 | 0.054 |
IBW = ideal body weight, OR = odds ratio.
Lactate clearance within 6 hr.
Dashes indicate statistical significance of p = 0.05.