TABLE 3.

Cerebral blood flow at baseline and at 12 wk in the intervention and control arms

	Intervention, mean ± SD (n = 18)			Control, mean ± SD (n = 9)
Brain region	Baseline	12 wk	Change	Baseline	12 wk	Change	P
Total gray matter	73.2 ± 9.1	75.1 ± 9.2	1.5 ± 10.4	76.4 ± 19.1	70.0 ± 15.4	−7.2 ± 11.4	0.08
Anterior cingulate cortex	76.3 ± 12.0	78.4 ± 11.8	1.7 ± 13.6	82.1 ± 20.7	78.5 ± 17.5	−4.8 ± 9.7	0.46
Caudate	50.8 ± 9.6	53.4 ± 10.3	2.1 ± 12.7	63.0 ± 31.8	46.8 ± 16.2	−18.3 ± 35.4	0.18
Frontal	92.5 ± 13.5	95.1 ± 13.5	2.0 ± 16.1	99.9 ± 29.8	88.0 ± 20.1	−13.1 ± 19.6	0.08
Middle frontal gyrus	107 ± 16.5	109 ± 16.9	1.4 ± 18.1	111 ± 31.9	101 ± 26.2	−10.9 ± 15.6	0.12
Hippocampus	41.2 ± 6.5	43.2 ± 7.3	1.8 ± 8.3	45.0 ± 14.1	37.6 ± 11.7	−7.8 ± 11.3	0.04a
Primary motor cortex	101 ± 16.9	104 ± 14.5	1.4 ± 17.2	111 ± 30.8	101 ± 24.8	−11.8 ± 21.3	0.25
Posterior cingulate cortex	92.1 ± 12.3	94.4 ± 12.7	1.5 ± 14.7	92.4 ± 23.0	93.6 ± 12.8	−5.6 ± 16.9	0.14
Pallidum	36.4 ± 6.7	38.2 ± 8.6	2.0 ± 10.4	43.2 ± 12.1	34.1 ± 8.9	−10.4 ± 15.4	0.31
Parietal	97.8 ± 14.7	102 ± 15.5	3.4 ± 16.4	98.6 ± 26.6	96.0 ± 27.2	−3.5 ± 8.8	0.27
Precuneus	88.9 ± 11.7	88.7 ± 16.7	−0.2 ± 14.2	95.2 ± 27.1	87.5 ± 23.1	−7.8 ± 14.6	0.20
Putamen	48.1 ± 9.4	48.4 ± 9.2	0.3 ± 14.3	57.4 ± 12.3	47.0 ± 11.8	−10.4 ± 14.3	0.58
Subparietal	98.5 ± 18.2	103 ± 20.4	3.4 ± 20.6	98.1 ± 30.4	96.6 ± 30.4	−1.9 ± 8.0	0.46
Temporal	57.3 ± 7.31	60.8 ± 8.8	3.0 ± 12.0	58.9 ± 14.9	53.3 ± 13.3	−6.0 ± 9.6	0.06
Thalamus	57.4 ± 10.1	61.9 ± 13.4	4.4 ± 10.8	59.9 ± 18.5	50.7 ± 14.4	−10.1 ± 15.3	0.002a

The P values were calculated using ANCOVA.

^aP < 0.05.