TABLE 6.

Neuropsychological test scores at baseline and 12 wk in the intervention and control arms

	Intervention, mean ± SD (n = 20)			Control, mean ± SD (n = 9)
Neuropsychological test	Baseline	12 wk	Change in score	Baseline	12 wk	Change in score	P
MMSE	28.4 ± 0.9	28.2 ± 1.6	−0.2 ± 1.5	28.9 ± 1.2	28.3 ± 1.8	−0.6 ± 1.2	0.64
MoCA	24.9 ± 2.3	26.2 ± 2.4	1.3 ± 2.4	26.4 ± 2.5	26.9 ± 1.7	0.4 ± 1.3	0.93
Trail making A, s	27.3 ± 8.4	24.2 ± 5.0	−3.1 ± 5.7	24.7 ± 5.5	22.1 ± 3.1	−2.4 ± 5.1	0.37
Trail making B, s	74.2 ± 26.0	65.3 ± 17.8	−8.8 ± 24.6	62.0 ± 11.6	59.7 ± 18.7	−2.7 ± 14.3	0.85
Logical memory IA	10.7 ± 2.7	12.0 ± 3.1	1.4 ± 2.9	10.3 ± 4.0	11.4 ± 5.3	1.2 ± 2.6	0.86
Logical memory IIA	9.8 ± 3.7	11.5 ± 3.4	1.7 ± 4.0	9.9 ± 4.1	11.3 ± 5.0	1.4 ± 2.9	0.87
Digit symbol	53.8 ± 12.0	56.3 ± 11.4	2.5 ± 5.4	56.4 ± 8.8	58.4 ± 7.7	2.0 ± 4.1	0.97
Digit span forward	8.9 ± 1.9	9.1 ± 2.0	0.2 ± 1.1	9.1 ± 2.3	9.4 ± 1.8	0.3 ± 0.9	0.66
Digit span backward	6.0 ± 2.2	6.2 ± 2.2	0.2 ± 1.4	7.6 ± 2.8	7.8 ± 2.3	0.2 ± 1.6	0.42
Category fluency animal	20.6 ± 5.9	22.6 ± 4.8	2.0 ± 5.4	19 ± 5.0	20.7 ± 3.0	1.7 ± 3.8	0.39
Category fluency vegetables	14.7 ± 3.4	13.6 ± 3.6	−1.2 ± 2.8	12.2 ± 3.1	14.4 ± 2.1	2.2 ± 2.6	0.03a
Block design	35.4 ± 12.4	39.2 ± 11.9	3.9 ± 4.1	40.1 ± 11.8	44.4 ± 12.0	4.3 ± 10.1	0.63
Stroop interference	36.6 ± 10.2	40 ± 12.2	3.4 ± 7.8	42.1 ± 7.1	41.9 ± 5.1	−0.1 ± 5.6	0.37
Free recall	11.0 ± 1.8	12.1 ± 2.5	1.0 ± 2.3	10.9 ± 2.4	11.2 ± 2.4	0.4 ± 1.7	0.13

The P values were calculated using ANCOVA.

^aP < 0.05.

MMSE, Mini-Mental State Examination; MoCA, Montreal Cognitive Assessment.