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. 2023 Jun 30;13:1134646. doi: 10.3389/fonc.2023.1134646

Table 2.

Comparison of quantitative MRI parameters between Ki-67 LIlow and Ki-67 LIhigh groups in the training set.

Low Ki-67 LI
(n = 35)
High Ki-67 LI
(n = 89)
p value ICC
Tumor size (cm) 3.15 [2.26, 4.36] 5.24 [2.62, 5.51] 0.002* 0.88
TLRAP 1.33 ± 0.25 1.38 ± 0.42 0.667 0.82
TEIAP 1.63 ± 0.31 1.73 ± 0.42 0.632 0.85
RTEAP 0.72 ± 0.41 0.80 ± 0.43 0.914 0.76
RERAP 0.84 [0.35, 1.05] 0.72 [0.42, 1.02] 0.445 0.80
TLRPVP 0.78 [0.83, 1.24] 0.84 [0.71, 1.13] 0.265 0.84
TEIPVP 1.23 [1.03, 1.42] 1.13 [0.95, 1.40] 0.232 0.77
RTEPVP 0.85 [0.52, 1.14] 0.70 [0.33, 1.11] 0.244 0.84
RERPVP 1.42 [0.89, 2.46] 1.04 [0.64, 1.84] 0.065 0.76
TLRTP 0.89 [0.78, 1.07] 0.78 [0.65, 0.95] 0.025* 0.83
TEITP 1.12 ± 0.23 1.17 ± 0.34 0.558 0.82
RTETP 0.74 ± 0.31 0.72 ± 0.36 0.830 0.80
RERTP 1.11 [0.75, 1.43] 0.95 [0.62, 1.23] 0.065 0.79
TLRHBP 0.67 ± 0.14 0.53 ± 0.16 0.004* 0.86
TEIHBP 0.78 ± 0.12 0.65 ± 0.15 0.026* 0.85
RTEHBP 0.37 [0.23, 0.54] 0.26 [0.14, 0.58] 0.314 0.87
RERHBP 0.45 [0.26, 0.68] 0.37 [0.24, 0.56] 0.058 0.81
T1Pre (msec) 1243.07 ± 257.41 1385.36 ± 239.28 0.047* 0.83
T1HBP (msec) 744.17 ± 162.74 845.21 ± 156.42 0.007* 0.82
ΔT1% 0.41 ± 0.14 0.38 ± 0.13 0.247 0.78

*p<0.05. Continuous variables are presented as median [inter-quartile range, IQR] or mean ± standard deviation. Categorial variables are presented as number (percentage).

AP, arterial phase; PVP, portal venous phase; TP, transition phase; HBP, hepatobiliary Phase; TLR, tumor to liver contrast ratio; TEI, tumor enhancement index; RTE, relative tumor enhancement; RER, relative enhancement ratio; Pre, pre-enhancement; T1Pre: pre-contrast T1 relaxation time; T1HBP, T1 relaxation time in the hepatobiliary phase; ΔT1%, reduction rate of T1 relaxation time; ICC, intraclass correlation coefficient.