Table 2.
Risk factors based on univariate analyses and multivariate COX analyses.
| Characteristics | Total(N) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
| Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | ||
| age | 797 | 1.137 (1.096-1.178) | <0.001 | 1.170 (1.111-1.232) | <0.001 |
| Gender | |||||
| male | 207 | Reference | |||
| female | 590 | 0.468 (0.209-1.047) | 0.064 | 0.758 (0.272-2.116) | 0.597 |
| stage | 797 | ||||
| Stage I | 480 | Reference | |||
| Stage II | 70 | 6.107 (1.226-30.425) | 0.027 | 0.535 (0.152-1.884) | 0.331 |
| Stage III | 159 | 9.489 (2.565-35.105) | <0.001 | 0.315 (0.119-0.831) | 0.020 |
| Stage IV | 2 | 149.583 (15.122-1479.623) | <0.001 | 0.218 (0.028-1.717) | 0.148 |
| Stage IVA | 70 | 11.226 (2.505-50.315) | 0.002 | 0.074 (0.017-0.329) | <0.001 |
| Stage IVB | 1 | 0.000 (0.000-Inf) | 0.998 | 1.000 (1.000-1.000) | |
| Stage IVC | 15 | 39.285 (9.329-165.430) | <0.001 | 868509.880 (188704.265-3997309.832) | <0.001 |
| T | 554 | ||||
| T1 | 70 | Reference | |||
| T2 | 175 | 0.900 (0.165-4.916) | 0.903 | 1.977 (0.641-6.093) | 0.235 |
| T3 | 184 | 1.082 (0.210-5.583) | 0.925 | 1.917 (0.674-5.454) | 0.223 |
| T4 | 10 | 10.661 (1.944-58.459) | 0.006 | 13.670 (4.399-42.481) | <0.001 |
| T4a | 14 | 5.292 (0.743-37.704) | 0.096 | 12.343 (2.764-55.114) | <0.001 |
| TX | 2 | 0.000 (0.000-Inf) | 1.000 | 0.000 (0.000-Inf) | 1.000 |
| M | 554 | ||||
| M0 | 332 | Reference | |||
| M1 | 9 | 5.181 (1.128-23.797) | 0.034 | 0.000 (0.000-0.000) | <0.001 |
| MX | 213 | 0.725 (0.247-2.130) | 0.559 | 0.760 (0.261-2.217) | 0.615 |
| N | 554 | ||||
| N0 | 238 | Reference | |||
| N1 | 100 | 0.876 (0.218-3.517) | 0.852 | ||
| N1a | 92 | 0.717 (0.144-3.555) | 0.684 | ||
| N1b | 75 | 2.137 (0.532-8.585) | 0.285 | ||
| NX | 49 | 2.156 (0.537-8.649) | 0.279 | ||
Bold values means significant difference, that is, p value < 0.05.