Table 2.

Univariate and multivariate logistic analyses.

	Univariate analysis		Multivariate analysis
	OR (95% CI)	P -value	OR (95% CI)	P -value
aCCI	1.313 (1.009–1.709)	0.043
Smoking history		0.000		0.042
Current smoking	5.340 (2.428–11.744)	0.000	3.764 (1.271–11.147)	0.017
Past smoking	3.263 (0.559–19.057)	0.189	3.796 (0.517–27.876)	0.190
Alcohol consumption	4.047 (1.851–8.848)	0.000
Cough	2.963 (1.437–6.109)	0.003	3.501 (1.258–9.739)	0.016
Dyspnea	2.608 (1.217–5.586)	0.014
RNA load	1.602 (1.136–2.258)	0.007
FERR	1.000 (1.000–1.000)	0.098
PCT	1.033 (0.933–1.144)	0.526
IL-6	2.363 (0.573–9.749)	0.234
APTT	1.021 (0.999–1.042)	0.057
LDH	1.000 (1.000–1.000)	0.866
BUN	1.139 (1.059–1.226)	0.000
Creatinine	1.014 (1.007–1.022)	0.000	1.012 (1.003–1.022)	0.010
FT4	0.926 (0.806–1.064)	0.277
TSH	0.588 (0.317–1.092)	0.093
MODS	7.393 (3.395–16.098)	0.000
ICU admission	12.1 (5.032–27.614)	0.000	4.100 (1.439–11.682)	0.008
Machined ventilation	5.625 (2.435–12.992)	0.000
Broad-spectrum antibiotic therapy ≥2	10.500 (4.736–23.277)	0.000	5.888 (2.095–16.543)	0.001
Corticosteroid use
Ever	4.020 (1.786–9.048)	0.001	4.631 (1.499–14.312)	0.008
< 1 mg/kg	2.193 (0.877–5.486)	0.093	4.455 (1.207–16.451)	0.025
≥1 mg/kg	11.063 (4.124–29.683)	0.000	4.819 (1.290–18.010)	0.019
≤ 5 d	3.668 (1.515–8.975)	0.004	3.833 (1.134–12.956)	0.031
>5 d	4.556 (1.749–11.869)	0.002	6.470 (1.638–25.556)	0.008