Table 9. The number of common-design variants detected by two NGS panels, classified for gene type, mean VAF, and concordance performance.
No. of common variant/s detected per gene | |||||||||
---|---|---|---|---|---|---|---|---|---|
Common variants identified ( n ) | Confirmed by the other NGS panel ( n ) | Mean VAF common variants (%) | PIK3CA | ERBB2 | KRAS | EGFR | BRAF | Common variants globally identified ( n ) | |
Panel 1 | 14 | 11 (79%) | 6.00 | 4 | 1 | 5 | 1 | 3 | 17 |
Panel 2 | 15 | 11 (73%) | 11.22 | 4 | 1 | 7 | 2 | 1 |
Abbreviations: cfDNA, circulating free DNA; NGS, next-generation sequencing; VAF, variant allele frequency.