Table 4.
Characteristics of eligible studies
| Source | Country | Study design | Participants’ mean age (year) | BMI (km/m2) | Body Weight (kg) | Study size 7-keto-DHEA/placebo |
Duration (weeks) | Outcome variables | 7-Keto-DHEA dosage (mg/d) |
|---|---|---|---|---|---|---|---|---|---|
| Kalman et al. [21] | USA | RCT | 44.5 | 31.9 | 91.6 | 13/10 | 8 | Body weight, body fat percentage | 200 (2 × 100) |
| Zenk et al. [20] | USA | RCT | 48.7 | 33.1 | 96.5 | 17/16 | 8 | Body weight, BMI, body fat percentage, BMR | 200 (2 × 100 mg) |
| Zenk et al. [3] | USA | RCT | 39.2 | 32.9 | 97.5 | 19/16 | 8 | Body weight, BMI, body fat percentage, RMR | 102 (2 × 51) |
| Zenk et al. [5] | USA | RCT | 38.5 | 32.2 | 93.7 | 40/40 | 5a | Body weight, BMI, body fat percentage, RMR | 200 (2 × 2 × 50) |
aEach of the three 7 day treatment period (7-keto-DHEA, HUM5007, placebo) was separated by a 7 day washout period