Table 2.
Univariate and multivariate COX regression analysis.
| Variables | Univariate COX regression analysis | Multivariate COX regression analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95%CI | p | HR | 95%CI | p value | |
| Pre-operative and intra-operative variables | ||||||
| Creatinine (μmol/L) | 1.004 | 1.002–1.007 | < 0.001 | |||
| Anhepatic phase (min) | 1.018 | 1.008–1.029 | 0.001 | 1.020 | 1.010–1.031 | < 0.001 |
| Hepatorenal syndrome | 0.352 | 0.178–0.695 | 0.003 | |||
| MELD | 1.033 | 1.009–1.057 | 0.008 | |||
| Age (year) | 1.033 | 1.007–1.060 | 0.012 | 1.027 | 1.001–1.053 | 0.039 |
| Prothrombin time | 1.460 | 1.068–1.994 | 0.017 | |||
| BMI | 1.093 | 1.016–1.175 | 0.018 | |||
| History of dialysis | 0.332 | 0.132–0.835 | 0.019 | |||
| Use of Entecavir | 1.915 | 1.080–3.397 | 0.026 | |||
| History of cerebrovascular disease | 0.364 | 0.145–0.912 | 0.031 | |||
| Use of Telbivudine | 0.593 | 0.355–0.991 | 0.046 | |||
| Post-operation variables | ||||||
| Length of stay in the care unit (days) | 1.002 | 1.001–1.003 | 0.001 | |||
| Laboratory findings at 30-day after LT | ||||||
| Cystatin C (mg/L) | 1.922 | 1.625–2.273 | < 0.001 | |||
| Urea nitrogen (mmol/L) | 1.078 | 1.056–1.100 | < 0.001 | |||
| Creatinine (μmol/L) | 1.005 | 1.003–1.006 | < 0.001 | |||
| eGFR (mL/min/1.73m2) | 0.978 | 0.971–0.984 | < 0.001 | 0.979 | 0.972–0.986 | < 0.001 |
| Uric acid (μmol/L) | 1.003 | 1.002–1.005 | < 0.001 | |||
| Triglyceride (mmol/L) | 1.358 | 1.189–1.551 | < 0.001 | 1.506 | 1.234–1.838 | < 0.001 |
| Fasting blood glucose (mmol/L) | 1.106 | 1.055–1.160 | < 0.001 | |||
| Hemoglobin (g/L) | 0.970 | 0.955–0.985 | < 0.001 | |||
| Albumin (g/L) | 0.931 | 0.881–0.985 | 0.012 | |||
| Low density lipoprotein cholesterol (mmol/L) | 0.641 | 0.446–0.919 | 0.016 | |||
Abbreviations: BMI Body mass index; eGFR Estimated glomerular filtration rate; HR Hazard ratio; MELD Model for end-stage liver disease; PT Prothrombin time.