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. 2023 Jul 14;13:11418. doi: 10.1038/s41598-023-38638-0

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Regular radiological healing process in HCS mice with femoral fracture. (a) Representative µCT images of the callus of WT and HCS mice 7, 14, and 21 days after osteotomy. Images were generated by SCANCO Medical microCT Analysis Software V6/10–2009, https://www.scanco.ch/images/Brochures/microct_sw_.v8.pdf, Brüttisellen, Switzerland (b) Quantification of bone volume (BV), tissue volume (TV) and bone volume per tissue volume (BV/TV). (c) Quantification of trabecular numbers (Tb.N.), trabecular thickness (Tb.Th.), and trabecular separation (Tb.Sp.) in the same groups. Non-parametric Mann–Whitney U test, *p < 0.05. Data are shown as mean with standard deviation. Data points indicate individual measurements from each mouse.