Figure 2.

Chromatin assembly defects in cac1∆ rtt106∆ are largely restored genome wide. (A–B) Genome-wide nucleosome profiles by MNase-seq of wild type and cac1∆ rtt106∆ cells synchronized in G1 and released into fresh medium for 60 min until G2. A representative nucleosome profile (A) and the occupancy profiles for all yeast genes aligned relative to the TSS (B) are shown. Cell cycle progression was followed by flow cytometry. The analysis was performed with two biological replicates.