Case 1 |
N = 54 |
N = 53 |
N = 52 |
Add low‐dose prednisone |
1 (1.9%) |
3 (5.7%) |
1 (1.9%) |
Continue current therapy and monitoring for now |
6 (11.1%) |
3 (5.7%) |
5 (9.6%) |
Increase dose of oral methotrexate |
6 (11.1%) |
7 (13.2%) |
10 (19.2%) |
Start a biologic therapy |
41 (75.9%) |
37 (69.8%) |
34 (65.4%) |
Switch methotrexate to leflunomide |
0 (0%) |
3 (5.7%) |
2 (3.8%) |
Case 2 |
N = 57 |
N = 52 |
N = 50 |
Continue current therapy and prescribe antidiarrheal medication |
8 (14.0%) |
11 (21.2%) |
10 (20.0%) |
Continue current therapy and reassess in 3 mo |
6 (10.5%) |
5 (9.6%) |
10 (20.0%) |
Start combination leflunomide and methotrexate at lower doses and stop sulfasalazine |
5 (8.8%) |
2 (3.8%) |
3 (6.0%) |
Stop sulfasalazine and start a biologic therapy |
35 (61.4%) |
32 (61.5%) |
26 (52.0%) |
Switch from leflunomide back to methotrexate at a lower dose and stop sulfasalazine |
3 (5.3%) |
2 (3.8%) |
1 (2.0%) |
Case 3 |
N = 53 |
N = 53 |
N = 53 |
Add hydroxychloroquine |
15 (28.3%) |
10 (18.9%) |
12 (22.6%) |
Add low‐dose prednisone |
1 (1.9%) |
1 (1.9%) |
3 (5.7%) |
Start a biologic therapy |
35 (66.0%) |
36 (67.9%) |
32 (60.4%) |
Switch methotrexate to leflunomide |
0 (0%) |
4 (7.5%) |
3 (5.7%) |
Continue current therapy and monitoring for now |
2 (3.8%) |
2 (3.8%) |
3 (5.7%) |
Case 4 |
N = 54 |
N = 53 |
N = 52 |
Add prednisone |
3 (5.6%) |
1 (1.9%) |
1 (1.9%) |
Start a biologic therapy |
50 (92.6%) |
52 (98.1%) |
50 (96.2%) |
Increase dose of methotrexate |
0 (0%) |
0 (0%) |
1 (1.9%) |
Switch methotrexate to leflunomide |
1 (1.9%) |
0 (0%) |
0 (0%) |