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. 2024 Jan 31;6:92. Originally published 2021 Apr 29. [Version 3] doi: 10.12688/wellcomeopenres.16749.3

Table 6. Various TDM methods and estimated commercial cost of equipment.

Method of TDM
(N = 50 studies)
Total N= 53
(%)
Estimated Cost of
Equipment
Auto-analyzer 3 (5.6) $14,000
Chemiluminescent Immunoassay 2 (3.7) Unknown
Enzyme Multiplied Immunoassay Technique 3 (5.6) $1600 (Cobas), $11,500 (Syva)
Fluorescence Polarization Immunoassay 22 (41.5) $1000 (TDx)
Gas Chromatography 2 (3.7) $79,500
High Performance Liquid Chromatography (HPLC) 9 (16.9) $21,500
HPLC with fluorescence detection 1 (1.8) $1799.99
HPLC with Ultraviolet detection (HPLC-UV) 5 (9.4) $2,695
Liquid Chromatography-Mass Spectrometry LC-MS 3 (5.6) $149,000
Reversed phase HPLC with UV detection 1 (1.8) $1100
Thin Layer Chromatography (TLC) 1 (1.8) Unknown
TLC with fluorescence detection 1 (1.8) Unknown