Table 2.

Summary of the diagnostic performance of the studies which explored the performance of Quidel Sofia SARS antigen Fluorescent Immunoassay (FIA) for diagnosing acute SARS-CoV-2 infections

Cohort	AUC (SE)	Sensitivity (95%CI)	Specificity (95%CI)
All samples	0.980 (0.01)	0.76 (0.74-0.78)	1.00 (1.00-1.00)
All samples (nasal swab)	0.987 (0.01)	0.72 (0.69-0.75)	1.00 (1.00-1.00)
Symptomatic patients	0.981 (0.02)	0.81 (0.77-0.83)	0.99 (0.99-0.99)
Symptomatic patients (nasal swab)	0.963 (0.05)	0.80 (0.77-0.93)	0.99 (0.99-1.00)
Asymptomatic patients	0.931 (0.01)	0.55 (0.46-0.61)	1.00 (1.00-1.00)
Asymptomatic patients (nasal swab)	0.888 (0.07)	0.45 (0.37-0.52)	1.00 (1.00-1.00)
Mixed cohorts	0.960 (0.03)	0.77 (0.75-0.80)	0.99 (0.99-1.00)