Table 4.
CTCAE grade 3 and 4 hematologic and hepatic toxicity after PHP in groupPRO (n=192), groupREDPRO (n=21) and groupNOPRO (n=43)
| Adverse event | CTCAE Grade 3-4 | |
|---|---|---|
| Value | % | |
| GroupPRO | ||
| Hematological toxicity | ||
| - Thrombopenia | 74 | 39 |
| - Leucopenia | 27 | 14 |
| - Anemia | 40 | 21 |
| Hepatologic toxicity | ||
| - AST increase | 27 | 14 |
| - ALT increase | 19 | 10 |
| - Hypoalbuminemia | 6 | 3 |
| - Hyperbilirubinemia | 7 | 4 |
| GroupREDPRO | ||
| Hematological toxicity | ||
| - Thrombopenia | 3 | 14 |
| - Leucopenia | 2 | 10 |
| - Anemia | 3 | 14 |
| Hepatologic toxicity | ||
| - AST increase | 2 | 10 |
| - ALT increase | 1 | 5 |
| - Hypoalbuminemia | - | - |
| - Hyperbilirubinemia | 1 | 5 |
| GroupNOPRO | ||
| Hematological Toxicity | ||
| - Thrombopenia | 10 | 23 |
| - Leucopenia | 4 | 9 |
| - Anemia | 8 | 19 |
| Hepatologic Toxicity | ||
| - AST increase | 6 | 14 |
| - ALT increase | 1 | 2 |
| - Hypoalbuminemia | 4 | 9 |
| - Hyperbilirubinemia | 1 | 2 |
CTCAE Common Terminology Criteria for Adverse Events, PHP Percutaneous hepatic perfusion, AST Aspartate transaminase, ALT Alanine transaminase