Table 6.
Determination of SER.DMP and DMP in Azstarys® capsules by the proposed methods and the reported method
| Parameters | SER.DMP | ||
|---|---|---|---|
| HPLC method | TLC densitometric method | Reported methoda [5] | |
| Number of measurements | 5 | 5 | 5 |
| Mean % recovery of SER.DMP | 100.43 | 99.68 | 99.43 |
| % RSD | 0.910 | 1.085 | 1.380 |
| Student’s t-testb | 1.153 (2.306) | 0.457 (2.306) | —— |
| F-valueb | 2.260 (6.388) | 1.606 (6.388) | —— |
| Parameters | DMP | ||
|---|---|---|---|
| HPLC method | TLC densitometric method | Reported methoda [5] | |
| Number of measurements | 5 | 5 | 5 |
| Mean % recovery of DMP | 100.43 | 99.68 | 99.43 |
| % RSD | 0.910 | 1.085 | 1.380 |
| Student’s t-testb | 1.153 (2.306) | 0.457 (2.306) | —— |
| F-valueb | 2.260 (6.388) | 1.606 (6.388) | —— |
a Reference method is HPLC using X-terra C18 column using a mixture of trifluoro acetic acid and acetonitrile (70:30 v/v) as mobile phase with a flow rate of 1 mL and UV-detection at 265 nm
b The values in parenthesis are tabulated values of “t” and “F” at (P = 0.05