Table 1. Baseline demographics and clinical characteristics of mother and infant population.
*Birth weight <750 g. †Data were not available for all patients.
ANS: antenatal steroids; BW: birth weight; C-section: cesarean section; DOL: days of life; IVH: intraventricular hemorrhage; Mg: magnesium; GA: gestational age; PNC: postnatal care; PROM: prolonged rupture of membranes
| Characteristics | IVH (Grade III or IV); N=17 | Non-IVH; N=14 | p-value |
| Maternal age (years), mean (SD) | 25.12 (5.42) | 28.71 (7.79) | 0.140 |
| Ethnicity†, n (%) | |||
| - White | 0 (0.00) | 2 (14.29) | 0.500 |
| - Black | 10 (76.92) | 8 (57.14) | - |
| - Hispanic | 3 (23.08) | 4 (28.57) | - |
| Sex of infant, n (%) | |||
| - Female | 7 (41.18) | 9 (64.29) | 0.200 |
| PNC†, n (%) | |||
| - Yes | 12 (80.0) | 11 (78.57) | 1.000 |
| - No | 3 (20.0) | 3 (21.43) | - |
| ANS, n (%) | |||
| - Yes | 10 (58.82) | 12 (85.71) | 0.132 |
| - No | 7 (41.18) | 2 (14.29) | - |
| Number of doses, n (%) | |||
| - 0 | 7 (41.18) | 2 (16.67) | 0.288 |
| - 1 | 5 (29.41) | 3 (25.00) | - |
| - 2 | 5 (29.41) | 7 (58.33 ) | - |
| Chorioamnionitis, n (%) | |||
| - Yes | 3 (17.65) | 2 (14.29) | 1.000 |
| - No | 14 (82.35) | 12 (85.71) | - |
| Antibiotic treatment, n (%) | |||
| - Yes | 10 (66.67) | 8 (57.14) | 0.597 |
| - No | 5 (33.33) | 6 (42.86) | - |
| Mg treatment, n (%) | |||
| - Yes | 4 (28.57) | 7 (53.85) | 0.182 |
| - No | 10 (71.43) | 6 (46.15) | - |
| Outborn, n (%) | |||
| - Yes | 10 (58.82) | 3 (21.43) | 0.036 |
| - No | 7 (41.18) | 11 (78.57) | - |
| PROM duration (hours), median (range) | 0 (0-240) | 0 (0 – 360) | 0.574 |
| C-section, n (%) | |||
| - Yes | 9 (52.94) | 10 (71.43) | 0.293 |
| - No | 8 (47.06) | 4 (28.57) | - |
| Multiple births, n (%) | |||
| - Yes | 6 (35.29) | 2 (14.29) | 0.240 |
| - No | 11 (64.71) | 12 (85.71) | - |
| BW (g), mean (SD) | 588.9 (94.99) | 610.40 (76.83) | 0.500 |
| GA (weeks), mean (SD) | 24.06 (1.44) | 24.36 (0.93) | 0.720 |
| Apgar 1-minute, n (%) | |||
| - Poor | 12 (80.0) | 10 (71.43) | 0.680 |
| - Good | 3 (20.0) | 4 (28.57) | - |
| Apgar 5-minute, n (%) | |||
| - Poor | 8 (53.33) | 6 (42.86) | 0.570 |
| - Good | 7 (46.67) | 8 (57.14) | - |
| Admission temperature (°C), median (range) | 36.60 (33.00-37.20) | 36.60 (35.80-37.00) | 0.790 |
| Surfactant use | |||
| - Yes | 60 (99.77) | 29 (100.00) | 1.00 |
| - No | 2 (3.23) | 0 (0.00) | - |
| DOL at the start of treatment, mean (SD) | 4 (1-52) | 5 (2-44) | 0.40 |