Fig. 1.

Prevalence of 11 minimally conscious state (MCS) items from the Coma Recovery Scale-Revised (CRS-R) in disorders of consciousness (DoC) patients from four different studies. Black , the prevalence of MCS items in the CRS-R in patients who transition from vegetative state/unresponsive wakefulness syndrome (VS/UWS) to MCS (adapted from Carrière et al ³⁰ ). Dark gray , the prevalence of MCS items in the CRS-R taking into account all MCS items observed in the whole cohort of MCS patients, and ( light gray ) when taking into account MCS items observed in patients who show only one sign of consciousness (adapted from Wannez et al ²⁹ ; in this study they included the first CRS-R where all MCS items were tested for every patient). In white, the frequency of CRS-R items is shown as temporally first ones to emerge in MCS patients (adapted from Martens et al ²⁸ ; evidence of transition to consciousness was defined as 2 consecutive complete CRS-R within 7 days indicating new MCS or emergence from MCS). Given the prevalence of MCS items in this figure from different studies, we highly encourage paying attention to these five most prevalent items (visual fixation, visual pursuit, reproducible movement to command, automatic motor response, and localization to noxious stimulation).