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. 2022 Dec 1;149(8):5405–5416. doi: 10.1007/s00432-022-04386-3

Table 1.

Baseline clinical characteristics of patients

Characteristic* HPT (n = 66) PTH (n = 56) PT (n = 41) P value
Age 52 (40–65) 52 (41–64) 57 (47–67) 0.074
Gender 0.416
Male 57 (86.36) 51 (91.07) 34 (82.93)
Female 9 (13.64) 5 (8.93) 7 (17.07)
PS 0.191
0 11 (16.67) 2 (3.57) 7 (17.10)
1 50 (75.76) 50 (89.29) 31 (75.60)
2 5 (7.58) 4 (7.14) 3 (7.30)
BMI 21.64 ± 3.07 21.09 ± 2.87 22.36 ± 3.42 0.135
HBV 0.191
Negative 12 (18.18) 4 (7.14) 5 (12.20)
Positive 54 (81.82) 52 (92.86) 36 (87.80)
Child–pugh 0.995
A 50 (75.76) 42 (75.00) 31(75.60)
B 16 (24.24) 14 (25.00) 10 (24.40)
AFP 0.199
 < 400 39 (59.09) 28 (50) 20 (48.78)
 ≥ 400 27 (40.91) 28 (50) 21 (51.22)
WBC 5.36 ± 2.20 5.83 ± 2.36 5.42 ± 2.08 0.475
HB 129.33 ± 21.99 130.16 ± 23.10 125.12 ± 22.53 0.519
PLT 149.90 ± 82.67 166.20 ± 88.09 162.39 ± 133.52 0.642
LYM 1.02 ± 0.52 1.13 ± 0.52 1.05 ± 0.46 0.516
TBIL 21.95 ± 14.53 22.06 ± 21.13 22.62 ± 22.83 0.984
ALT 71.43 ± 60.36 81.45 ± 65.30 68.03 ± 48.59 0.494
AST 48.36 ± 38.23 51.43 ± 41.95 41.86 ± 32.24 0.471
ALB 38.83 ± 7.98 36.76 ± 6.75 36.44 ± 5.34 0.14
LDH 234.39 ± 156.42 326.23 ± 699.87 226.84 ± 128.55 0.414
PT 12.31 ± 1.67 12.23 ± 1.84 12.52 ± 1.37 0.701
Liver cirrhosis 0.231
Absent 44 (66.67) 43 (76.79) 33 (80.50)
Present 22 (33.33) 13 (23.21) 8 (19.50)
Tumor thrombus 0.777
Absent 41 (62.12) 29 (51.79) 25 (61.00)
Branch of portal vein 4 (6.06) 3 (5.36) 2 (4.90)
Main portal vein 21 (31.82) 24 (42.86) 14 (34.1)
Extrahepatic metastasis 0.328
Absent 37 (56.06) 27 (48.21) 17 (41.5)
Present 29 (43.94) 29 (51.79) 24 (58.5)
Smoker 0.994
Never 48 (72.72) 40 (71.43) 29 (70.70)
Previous 9 (13.64) 7 (12.50) 6 (14.60)
Now 9 (13.64) 9 (16.07) 6 (14.60)
Alcoholism 0.403
Never 49 (74.24) 47 (83.93) 34 (82.90)
Previous 9 (13.64) 6 (10.71) 2 (4.90)
Now 8 (12.12) 3 (5.36) 5 (12.20)
Surgery 0.653
Yes 18 (27.27) 17 (30.36) 9 (22.00)
No 48 (72.73) 39 (69.64) 32 (78.00)
Radiotherapy 0.827
Yes 9 (13.64) 6 (10.71) 6 (14.60)
No 57 (86.36) 50 (89.29) 35 (85.40)

HPT initial hepatic artery intervention combined with immunotarget therapy; PTH immunotarget therapy sequential hepatic artery interventional therapy; PT immunotarget therapy only

*No (%)