Table 3.
Staining results and correlation analysis
| RIG-I | EFTUD2 | |||||||
|---|---|---|---|---|---|---|---|---|
| Median IRS (± SD) |
% | p (NPAR) | ρ | Median IRS (± SD) |
% | p (NPAR) | ρ | |
| FIGO1 | ||||||||
|
FIGO I FIGO II FIGO III FIGO IV |
6.4 (± 2.6) 6.7 (± 2.9) 8.0 (± 2.7) 9.0 (± 3.4) |
/* 6.7 11.1 0 |
0.027 | 0.201 |
6.0 (± 3.1) 4.3 (± 2.7) 5.8 (± 3.4) 6.3 (± 3.2) |
7.5 6.7 /* 0.0 |
0.815 | − 0.044 |
| pT2 | ||||||||
|
T1 T2/3/4 |
6.7 (± 2.6) 7.5 (± 3.0) |
2.3 2.0 |
0.010 | 0.174 |
6.00 (± 3.1) 5.7 (± 3.1) |
7.7 8.2 |
0.928 | 0.006 |
| Grade1 | ||||||||
|
G1 G2 G3 |
6.0 (± 2.6) 7.8 (± 2.4) 8.5 (± 3.7) |
10.3 /* 0 |
0.007 | 0.210 |
5.7 (± 3.1) 6.0 (± 3.2) 6.8 (± 3.5) |
3.2 10.7 /* |
0.303 | 0.096 |
| pN2 | ||||||||
|
N − N + |
6.7 (± 2.7) 8.0 (± 2.9) |
1.4 19.0 |
0.753 | 0.110 |
6.0 (± 3.1) 5.7 (± 3.5) |
8.0 4.8 |
0.657 | − 0.035 |
| pM2 | ||||||||
|
M − M + |
7.0 (± 2.5) 5.3 (± 4.5) |
6.5 20.0 |
0.539 | 0.025 |
5.5 (± 3.1) 6.7 (± 4.3) |
/* 20.0 |
0.464 | 0.102 |
SD standard deviation, % percentage of the subgroup with median IR, NPAR non-parametric test, p p value, ρ correlation coefficient. 1correlation tested by Kruskall–Wallis test (p; NPAR) and Spearman-correlation (ρ).2correlation tested by Mann–Whitney test (p; NPAR) and Spearman-correlation (ρ).
FIGO: classification of the International Federation of Gynecology and Obstetrics (FIGO I: The cancer is found only in the uterus; FIGO II: The tumor has spread from the uterus to the cervical stroma but not to other parts of the body; FIGO III: The cancer has spread beyond the uterus, but it is still only in the pelvic area; FIGO IV: The cancer has spread to the mucosa of the rectum or bladder or the cancer has spread to lymph nodes in the groin area, and/or it has spread to distant organs, such as the bones or lungs). pT: Tumor size (pT1: The cancer is found only in the uterus; pT2: The tumor has spread from the uterus to the cervical stroma but not to other parts of the body; pT3: The cancer has spread beyond the uterus, but it is still only in the pelvic area; pT4: The cancer has spread to the mucosa of the rectum or bladder). pN: status regarding lymph node. pN0: histopathological lymphnodes without cancer infiltration. pN1: histopathological lymphnodes with cancer infiltration. pM: status regarding distant metastasis. pM0: histopathological examination without sign for distant metastasis. pM1: histopathological examination with sign for distant metastasis. *Values resulted from calculations, no sample with this value exists. Significant results are shown in bold