Table 4.
The correlation analyses between NLR and clinical symptoms, onset profile as well as the CANTAB neurocognitive test results in FEP patients.
| Variables of interest | Spearman's rho (ρ) | p-value |
|---|---|---|
| Clinical symptoms | ||
| PANSS-positive symptom score b | 0.613 | * < 0.001 |
| PANSS-disorganization score b | 0.566 | *0.002 |
| PANSS-negative symptom score b | 0.272 | *0.17 |
| PANSS-excitation score b | 0.628 | * < 0.001 |
| PANSS-anxiety and depressive symptom score b | 0.435 | *0.023 |
| CGI-S score | 0.644 | * < 0.001 |
| Onset profile | ||
| Log DUPa | − 0.296 | 0.134 |
| Neurocognitive tests | ||
| Verbal memory | ||
| VRM-FR | 0.063 | 0.755 |
| VRM-IR | − 0.156 | 0.438 |
| VRM-DR | − 0.139 | 0.49 |
| Executive function | ||
| SWM-BE | 0.145 | 0.471 |
| SWE-S | − 0.035 | 0.861 |
| OTS-PSFC | − 0.188 | 0.348 |
| OTS-MLC | 0.066 | 0.744 |
aDUP was log-transformed for parametric analysis due to its skewed distribution.
bPANSS positive, disorganization, negative, excitation, anxiety and depressive symptom scores were derived on the basis of a previous factor-analytic study on FEP patients35.
PANSS, Positive and Negative Syndrome Scale; CGI-S, Clinical Global Impression-Severity; DUP, duration of untreated psychosis; VRM, Verbal recognition memory test, -FR, free recall, -IR, immediate recognition, -DR, delayed recognition; SWM, Spatial working memory test, -BE, between errors, -S, strategy; OTS, One-touch stockings of Cambridge test, -PSFC, Number of problems solved on first choice, -MLC, median latency to first choice.
*Denotes p < 0.05.
Significant values are in bold.