Skip to main content
. 2023 Jul 15;14:4232. doi: 10.1038/s41467-023-39804-8

Fig. 6. Histone modifications, the small RNAs pathway and neuropeptide secretion are involved in the inheritance of the acquired cellular changes.

Fig. 6

A Quantification of the acquired cellular changes in histone modifying mutants as evident by the translocation of DAF-16/FOXO to cells’ nuclei following exposure to the CS IAA. B Quantification of the acquired cellular changes in mutants, defective in genes involved in small RNA processing and neuropeptide secretion, as evident by the translocation of DAF-16/FOXO to cells’ nuclei following exposure to the conditioned stimulus IAA. For each group, N = 3 biologically independent experimental repeats, each scoring ∼50 animals. Significance comparisons are between trained and mock-trained animals. P-values from left to right: A 6.7E−14, 0.86, 3.8E−19, 0.91, 1.6E−13, 0.42, 7.2E−15, 1.7E−10, 1.8E−6, 1.4E−4. B 1.2E−11, 0.62, 0.53, 0.08, 7.8E−3, 5.9E−6, 1.2E−9, 0.17, 5.2E−10, 0.6. *p < 0.05, ***p < 0.0005 (two-sided proportion test after Bonferroni correction). N.S not significant. Error bars denote SEM. Source data is provided as a Source Data file.