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. 2023 Jul 15;14:4236. doi: 10.1038/s41467-023-39987-0

Table 1.

The occupancy and B-factor of the molecules in the selectivity filter

z(Å) NavAb N49K L176QNK L176GNK
Na Ca Na Ca Na Ca
7.5 Molecule (occupancy/B-factor) H2O (0.25/61.97)
5 SiteHFS The carbon of the 177th carboxyl group
(1.00/53.03) (1.00/42.17) (1.00/16.17) (1.00/19.77) (1.00/94.29) (1.00/36.17)
2.5 Molecule (occupancy/B-factor) Na+ (0.15/62.21) Ca2+ (0.2/85.85) Na+ (0.16/42.76) H2O (0.25/25.10) Na+ (0.25/114.3) H2O (0.25/97.41)
0 SiteCEN The oxygen of the 176th main chain carbonyl group
(1.00/58.83) (1.00/30.65) (1.00/33.16) (1.00/19.44) (1.00/133.9) (1.00/54.17)
−1.5 Molecule (occupancy/B-factor) Na+ (0.25/67.47) Ca2+ (0.25/44.40) Na+ (0.25/149.1) Ca2+ (0.25/103.0)
−2.5 SiteIN The oxygen of the 175th main chain carbonyl group
(1.00/67.04) (1.00/44.15) (1.00/31.11) (1.00/29.31) (1.00/127.8) (1.00/58.30)
−5 Molecule (occupancy/B-factor) The oxygen of the L176Q side chain carbonyl group H2O (1.00/114.6) H2O (1.00/50.08)
(1.00/44.94) (1.00/41.00)
H2O (1.00/41.54) Ca2+ (1.00/41.33) Ca2+ (1.00/113.9)