Table 2.
Aldose reductase, BUCHE, COX-II and SARS-CoV-2 Mpro inhibitory activities of the essential oil of Araucaria heterophylla oleogum resin compared to standards.
| Sample | Aldose reductase IC50 µg/mL | Sample | BUCHE IC50 µg/mL |
|---|---|---|---|
| EO | 0.133 ± 0.006 | EO | 0.154 ± 0.009 |
| Epalrestat (standard) | 0.165 ± 0.008 | Rivastigmine (standard) | 0.078 ± 0.005 |
| Sample | COX-II IC50 µg/mL | Sample | SARS-CoV-2 Mpro IC50 µg/mL |
|---|---|---|---|
| EO | 10.3 ± 0.29 | EO | 32.1 ± 1.44 |
| Celecoxib (standard) | 2.6 ± 0.09 | Tipranavir (standard) | 4.7 ± 0.21 |
All data are presented as mean value ± SD for three independent experiments.