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. Author manuscript; available in PMC: 2024 Oct 1.
Published in final edited form as: Ophthalmic Epidemiol. 2023 Jan 16;30(5):523–531. doi: 10.1080/09286586.2023.2168014

Table 2.

Association between race and incidence of severe ROP, incidence of any ROP, and incidence of plus disease

Incidence of Severe ROP Incidence of Any ROP Incidence of Plus disease
Maternal race N of
infants
N of severe
ROP (%)
Adjusted risk
ratio*
(95%CI)
P N of any
ROP (%)
Adjusted Risk
ratio*
(95% CI)
P N of plus
disease (%)
Adjusted Risk
ratio*
(95% CI)
P
All infants <0.001 <0.001 <0.001
White 5580 694 (12.4%) 1.00 2411 (43.2%) 1.00 350 (6.3%) 1.00
Black 3252 360 (11.1%) 0.69 (0.62, 0.77) <0.001 1370 (42.1%) 0.83 (0.80, 0.87) <0.001 118 (3.6%) 0.44 (0.37, 0.54) <0.001
Asian 353 42 (11.9%) 1.05 (0.83, 1.34) 0.68 108 (30.6%) 0.77 (0.68, 0.87) <0.001 21 (5.9%) 1.04 (0.70, 1.53) 0.85
 
Gestational age <28 weeks <0.001 <0.001 <0.001
  White 2202 635 (28.8%) 1.00 1678 (76.2%) 1.00 322 (14.6%) 1.00
  Black 1532 345 (22.5%) 0.71 (0.64, 0.78) <0.001 1063 (69.4%) 0.87 (0.84, 0.90) <0.001 114 (7.4%) 0.46 (0.37, 0.56) <0.001
  Asian 115 38 (33.0%) 1.06 (0.83, 1.35) 0.65 77 (67.0%) 0.86 (0.76, 0.96) 0.01 21 (18.3%) 1.14 (0.77, 1.68) 0.51
 
Gestational age ≥28 weeks 0.005 <0.001 0.001
  White 3378 59 (1.7%) 1.00 733 (21.7%) 1.00 28 (0.8%) 1.00
  Black 1720 15 (0.9%) 0.45 (0.25, 0.79) 0.005 307 (17.8%) 0.76 (0.67, 0.85) <0.001 4 (0.2%) 0.25 (0.09, 0.71) 0.009
  Asian 238 4 (1.7%) 1.08 (0.40, 2.94) 0.88 31 (13.0%) 0.64 (0.47, 0.88) 0.006 0 (0.0%) ND

CI=Confidence interval.

*

Adjusted by birth weight, gestational age and gender.