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[Preprint]. 2023 Nov 13:2023.07.01.547348. [Version 3] doi: 10.1101/2023.07.01.547348

Figure 5. SORL1 R953C cells are defective in maturation and shedding of the SORL1 protein.

Figure 5.

(a) Representative western blotting of lysate and media samples from HEK293 cells transiently transfected with SORLA-WT or SORLA-R953C. (b) Densitometric analysis from HEK293 and N2a samples. The signal for the R953C is expressed relative to the WT signal. Results are expressed as Mean± SD and analyzed by parametric two-tailed paired t-test. Significance was defined as a value of **p<0. 01, ***p<0. 001. n= 4 independent experiments