Table 7. Gene Ontology (GO) analysis, LPS induced microglia.

All differentially expressed proteins and phosphoproteins were used to determine GO terms. Only the most significant terms are shown. For the complete list, see Additional file 7: Table S5.

GO term	LPS Microglia Proteomics: Biological Processes	P-value
GO:0032715	negative regulation of interleukin-6 production	3.23E-05
GO:0072310	glomerular epithelial cell development	3.44E-05
GO:0072015	glomerular visceral epithelial cell development	3.44E-05
GO:0034446	substrate adhesion-dependent cell spreading	1.08E-04
GO:0015850	organic hydroxy compound transport	1.39E-04
GO:0031589	cell-substrate adhesion	1.63E-04
GO:0072359	circulatory system development	1.90E-04
GO:2000351	regulation of endothelial cell apoptotic process	2.08E-04
GO:0003014	renal system process	2.51E-04
GO:0006003	fructose 2,6-bisphosphate metabolic process	3.31E-04
GO term	LPS Microglia Phosphoproteomics: Biological Processes	P-value
GO:0008380	RNA splicing	2.32E-20
GO:0000398	mRNA splicing, via spliceosome	2.89E-19
GO:0051056	regulation of small GTPase mediated signal transduction	5.17E-18
GO:0006397	mRNA processing	1.37E-17
GO:0035556	intracellular signal transduction	1.56E-17
GO:0006338	chromatin remodeling	3.11E-13
GO-0006325	chromatin organization	2.14E-12
GO:0006468	protein phosphorylation	3.52E-11
GO:0007010	cytoskeleton organization	1.22E-10
GO:0006974	cellular response to DNA damage stimulus	2.18E-10
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	2.86E-10
GO:0051301	cell division	4.59E-09
GO:0030036	actin cytoskeleton organization	9.04E-09
GO:0007165	signal transduction	1.01E-08
GO:0090630	activation of GTPase activity	2.75E-08