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. Author manuscript; available in PMC: 2023 Jul 16.
Published in final edited form as: Nat Metab. 2021 Feb 18;3(2):244–257. doi: 10.1038/s42255-021-00349-z

Extended Data Fig. 6 |. Metabolomics grouping by genotype highlighting top altered detected compounds.

Extended Data Fig. 6 |

a, Ortho PLS-DA plots each point represents an individual sample of mouse liver from 20 weeks on HFD, and how similar that sample is per all detected compounds compared to others run. eIF4e+/− liver samples clustered similar and separate from WT liver samples (n = 3, 5 respectively). b, Heatmap depicting the top 10% of metabolites increased or decreased across those detected (64/320). Lipids and carnitines showed strongest trend.