Table 3.
Characteristics of the included bone lesions
| Characteristic of bone lesions | Metastatic (n = 305) number (%) | Benign (n = 204) number (%) | Odds ratio (95% CI) | p value |
|---|---|---|---|---|
| Site of detected lesion | ||||
| Pelvis | 127 (41.6) | 91 (44.6) | NA | NA |
| Vertebrae | 70 (23.0) | 57 (27.9) | ||
| Rib | 42 (13.8) | 32 (15.6) | ||
| Humerus | 11 (3.6) | 4 (2.0) | ||
| Femur | 20 (6.5) | 12 (5.9) | ||
| Scapula | 19 (6.2) | 4 (2.0) | ||
| Skull | 7 (2.3) | 0 (0) | ||
| Sternum | 7 (2.3) | 2 (1.0) | ||
| Clavicle | 2 (0.7) | 2 (1.0) | ||
| Nature | ||||
| Purely lytic | 21 (6.9) | 16 (7.8) | NA | 0.696* |
| Purely sclerotic | 174 (57.1) | 175 (85.8) | ||
| Mixed | 16 (5.2) | 13 (6.4) | ||
| No underlying CT finding | 94 (30.8) | – | ||
| Soft tissue component | 17 (5.6) | 4 (2.0) | 3.0 (1.0–8.9) | 0.044 |
| Ill-defined lesion | 99 (32.5) | 30 (14.7) | 2.8 (1.8–4.4) | < 0.001 |
| Size > 1 cm | 161 (85.6) | 68 (33.3) | 2.2 (1.5–3.2) | < 0.001 |
| Cortical destruction | 24 (7.9) | 7 (3.4) | 2.4 (1.0–5.7) | 0.040 |
| Asymmetric growth | 132 (43.3) | 74 (36.3) | NA | 0.114 |
| Mean Hounsfield unit | 537 ± 244.3 | 809.4 ± 376.5 | NA | < 0.001 |
Bolded p-values are < 0.05
*p value was calculated among the lesions that had underlying CT finding
*NA not applicable