Table 1.

Physiological parameters in rats during 6 h of Sevoflurane Anesthesia. SpO₂, heart rate, and respiration were recorded in PND7 rat pups at the cessation of the 6-h experiments. As expected, 6-h sevoflurane anesthesia resulted in decreased heart rate and respiration compared with control pups. No signs of moderate (SpO₂ <95%) or severe (SpO₂ <90%) hypoxia were observed. Within 30 min of anesthesia cessation, anesthetized pups fully recovered and responded vigorously to tail and toe pinch.

Physiological parameters	Control	Sevoflurane
SpO2	99.18 ± 0.08	97.34 ± 0.41
Heart rate (beats per minute)	376.5 ± 14.50	148.9 ± 4.42
Respiration (breaths per minute)	95.08 ± 3.58	34.33 ± 3.67