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Downregulation of SMOC2 regulated autophagy in HF rats. (a) Western blotting showed the expression of autophagy-related markers (LC3 II/I, Beclin-1, and p62) in HF rats after SMOC2 knockdown. (b) TEM showed the state of autophagy in HF rats after SMOC2 knockdown (scale bar = 2 µm). **P < 0.01 compared to sham group; ## P < 0.01 compared to HF + sh-NC group.
