Scheme 3. Synthesis of Rimomycin A Analogues 16 and 17.
(a) Boc-Ahx-NHS, DMSO/DMF, TEA, 20 h at RT; (b) N,N-dimethylamino propylamine (5 equiv), PyBop, NMM (30 equiv) 2 h at RT; (c) DCM/TFA (1:1), 20 min, RT.
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