(a) DCAF1 crystal structure
in complex with 8 (PDB
ID: 8OGB, purple) overlaid with the DCAF1 crystal structure in complex
with 1 (PDB ID: 8OG6, cyan). (b) DCAF1 crystal structure
in complex with 11 (PDB ID: 8OGC, yellow) overlaid with
the DCAF1 crystal structure in complex with 8 (purple),
of which only the ligand is shown. The DCAF1 protein surface is shown
in gray, and the hydrogen bonds are shown as dashed black lines.