Figure 2.
Inhibition of currents through high-voltage-activated calcium channels by acute hypoxia in retina ganglion cells. (A) The bar graph of the mean normalized values of calcium currents in control (black) and during the hypoxia (red); ***p < 0.001 compare to control. (B) Representative recordings of calcium currents under control, 60 s of hypoxia, and reoxygenation. The corresponding normalized currents are plotted above the recording. (C) The dynamic of averaged, normalized calcium currents amplitudes during control, 60 s of hypoxia (red), and reoxygenation (blue). (D) I–V relationships of averaged normalized calcium current amplitudes in control (black) and during hypoxia (red). The corresponding G–V curve of HVA calcium channels was built for control (black) and hypoxia (red). The solid lines are fitted with the Boltzmann curve.
