Table 2.

Univariable and multivariable Cox regression analysis of clinical characteristics and ZEB1 expression

Variable	Univariate analysis			Multivariate analysis
	HR	95% CI	P value	HR	95% CI	P value
ZEB1
Positive vs Negative	8.63	3.14–23.76	0.00003	5.82	1.82–18.58	0.003
Age
> 16 years vs ≤ 16 years	1.23	0.53–2.84	0.62871
Gender
Female vs Male	0.84	0.36–1.96	0.67883
Relapse
Yes vs No	4.97	2.13–11.61	0.00021	0.94	0.30–2.95	0.911
Metastasis
Yes vs No	8.08	3.12–20.93	0.00002	12.05	1.28-113.05	0.029
TNM stage
I vs II/III	0.19	0.08–0.47	0.00034	2.14	0.30-15.47	0.045
Location
Femur/Tibia vs Else	0.47	0.17–1.29	0.14147	0.93	0.30-2.86	0.895
Tumor size
> 6 cm vs ≤ 6 cm	0.53	0.22–1.26	0.14862	0.84	0.32-2.21	0.722