Table 6.
Multivariate Cox regression analyses for composite of all cause death, non-fatal MI, coronary artery, revascularization and stroke
| METS-IR | HR (95% CI) | |||
|---|---|---|---|---|
| Composite of all-cause death | Non-fatal MI | Coronary artery revascularization | Stroke | |
| Per 1 unit increase | 1.03 (1.00–1.07) | 1.05 (1.01–1.09) * | 1.05 (1.01–1.09) * | 1.06 (1.02–1.10) * |
| Per 1 SD increase | 1.23 (0.97–1.55) | 1.37 (1.07–1.77) * | 1.36 (1.03–1.79) * | 1.46 (1.14–1.80) * |
| Quartile 1 | 1 (Reference) | 1 (Reference) | 1 (Reference) | 1 (Reference) |
| Quartile 2 | 0.77 (0.38–1.55) | 0.99 (0.47–2.11) | 1.09 (0.48–2.47) | 1.56 (0.64–3.77) |
| Quartile 3 | 1.12 (0.57–2.23) | 0.95 (0.44–2.03) | 1.26 (0.56–2.84) | 2.23 (0.96–5.21) |
| Quartile 4 | 1.33 (0.69–2.55) | 2.14 (1.08–4.22) * | 1.79 (0.82–3.92) | 3.56 (1.56–8.15) * |
| p for trend | 0.276 | 0.027 | 0.122 | 0.001 |
Adjusted for age, gender, previous MI, previous stroke, previous PCI, admission for MI, hypertension, DM, hyperlipidemia, FH-CAD, TC, LDL-C, eGFR, LVEF, antiplatelet drugs, beta-blockers, statins, ACEI/ARB and hypoglycemic drugs
METS-IR the metabolic score for insulin resistance, MI myocardial infarction, HR hazard ratio, CI confidence interval, SD standard deviation
p values in bold are < 0.05
*p < 0.05