Table 2.

Advantages and disadvantages of different elements for antibacterial CDT.

Metal element for antibacterial CDT	Advantages	Disadvantages
Fe	Various sources, high catalytic activity, and low cost	Narrow optimal pH range (2–4) for the Fenton reaction
Cu	A broader pH range for the Fenton-like reaction, high catalytic activity, and wound healing promotion capacity	Potential of heavy metal poisoning
Mn	Manganese oxides have the advantages of simple preparation, low cost, and low biological toxicity; in addition, the existence of several valence states of Mn makes manganese oxide an excellent catalyst.	Possible requirement of HCO3−
Co	High catalytic activity	Toxicity of excessive Co ions
Ni	Good biocompatibility, prominent photothermal performance (for promoting CDT), and excellent biodegradability	Complexes containing Ni2+ have short triplet lifetimes and a weak ROS generation ability
Ag	Inherent antibacterial effect	Requirement of increased H+ amount in the environment
Ru	High catalytic activity and stability	High cost